Level 2

Chemical Name :Bromate

CAS Registry Number: 15541-45-4

Cancer Oral Risk Values

Click on green circle(s) for more information.

Organization Name	ATSDR	Health Canada	IARC	IPCS	IPRV	ITER PR	NSF Intl	RIVM	TCEQ	U.S.EPA
Risk Value Name										RSD
Risk Value (mg/kg-day)										1.4E-5
Year										2001
Classification										B2
Target Organ										kidney, testis, thyroid tumors
Species										rat
Study										DeAngelo et al., 1998
More Information

Synopsis

U.S. EPA has evaluated the carcinogenicity of bromate. EPA classifies this chemical as B2 - probable human carcinogen under its current guidelines (U.S. EPA 1986). The cancer weight of evidence classification is based on all routes of exposure. Under its "Proposed Guidelines for Carcinogen Risk Assessment" (U.S. EPA, 1996), EPA determined that bromate should be evaluated as a likely human carcinogen by the oral route of exposure. EPA estimated an oral slope factor of 7E-1 per (mg/kd-day). TERA has converted the EPA oral slope factor to a risk specific dose (RSD) at the 1 in 100,000 level. The EPA value is converted by dividing 1E-5 by the slope factor of 7E-1 per (mg/kg)/day to determine a RSD of 1.4E-5 mg/kg-day. Click on the green circle(s) for more information.

---

Glossary of ITER definitions

ITER Instructions

---

All contents © 1997 - 2013 Concurrent Technologies Corporation and TERA.
All rights reserved.

---